Customized HFP, innovative and comfortable macular pigment evaluation

The MacuLux®PROFILER is a densitometer for the assessment of the macular density of the eye. Densitometers by the American manufacturer MACULARMETRICSII have been used by leading researchers around the world in hospitals, research and industrial laboratories, including the National Eye Institute (NEI) and Macular pigment research centers in Waterford (Ireland) and Athens (Georgia, USA).
A majority of the knowledge we have about macular pigment today is based on research done with this very densitometer technology! Now ebiga®VISION is making this latest model of the
densitometer available for European researchers and ‚state-of-the-art‘ -eye-doctors.

How does the MacuLux®Profiler work?
MacuLux®Profiler works on the basis of the principles of customized heterochromatic flicker photometry (cHFP). This technology takes advantage of the spatial distribution of the macular pigment and its spectral absorption properties.
Pigment density is the most concentrated in the center of the macula and declines exponentially to the eccentricity up to a value of about 6-8° eccentricity. At this level, it can no longer be determined optically.
Nutritional, environmental factors and diseases like Diabetes,Glaucoma and AMD do have an impact on the entire pigment distribution and increase or reduce the optical density of the
pigment. In order to evaluate the quality of the macular pigment, the MacuLux®Profiler is used to analyze the most centrally located area of the macula, i.e. at eccentricity of 0.5° and 0.25°.
The optical density of this foveal zone is determined in relation to the base line on an eccentric location (7°).

MPOD (~Makulapigmentdichte) in Abhängigkeit zur Entfernung vom Zentrum der Makula (in Grad der Exentrizität) nach Hammond B.R. 1997

MacuLux®Profiler Processes
The test subject will have to undergo test series for the fovea and for the parafovea. When he/she looks through the ocular, he/she will always see a non-flickering test field. When the patient perceives a flicker, he acknowledges this by pressing his test button.
This flickering sensation is generated by alternating flashes of blue and green light, specifically between 460 nm (blue) of the wave length with maximum absorption by the macular pigment and 550 nm (green) of the reference wave length, which is not being absorbed by the macular pigment.
The increase in the amount of blue light necessary for absorption by the pigment is the measure of the optical density.
After the determination and the calculation of the reference in the pigmented area of the Parafovea at 7°, the device indicates the optical density of the macular pigment (MPOD).

customized heterochromatic flicker photometry (cHFP) and MPOD*
*MPOD = Macular Pigment Optical Density


2.)Densitometer_References Publications