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Customized HFP, innovative and comfortable
macular pigment evaluation.

 

 

The MacuLux®PROFILER is a densitometer for the assessment of the

macular density of the eye. Densitometers by the American manufacturer

MACULARMETRICSII have been used by leading researchers around the

world in hospitals, research and industrial laboratories,

including the National Eye Institute (NEI) and Macular pigment research

centers in Waterford (Ireland) and Athens (Georgia, USA).

A majority of the knowledge we have about macular pigment

today is based on research done with this very densitometer

technology!

Now ebiga®VISION is making this latest model of the densitometer

available for European researchers and ‚state-of-the-art‘-eye-doctors.

 

 

How does the MacuLux®Profiler work?

 

MacuLux®Profiler works on the basis of the principles of

customized heterochromatic flicker photometry (cHFP).

This technology takes advantage of the spatial distribution of the

macular pigment and its spectral absorption properties.

Pigment density is the most concentrated in the center of the

macula and declines exponentially to the eccentricity up to a

value of about 6-8° eccentricity. At this level, it can no longer be

determined optically.

Nutritional, environmental factors and diseases like Diabetes,

Glaucoma and AMD do have an impact on the entire pigment

distribution and increase or reduce the optical density of the

pigment.

In order to evaluate the quality of the macular pigment,

the MacuLux®Profiler is used to analyze the most centrally

located area of the macula, i.e. at eccentricity of 0.5° and 0.25°.

The optical density of this foveal zone is determined in relation to

the base line on an eccentric location (7°).

 


MacuLux®Profiler Processes

 

The test subject will have to undergo test series for the fovea and

for the para-fovea. When he/she looks through the ocular, he/she

will always see a no-flickering test field. Once flicker occours the

test person press the bottom.

This flickering sensation is generated by alternating flashes of blue

and green light, specifically between 460 nm (blue) of the wave

length with maximum absorption by the macular pigment and

550 nm (green) of the reference wave length, which is not being

absorbed by the macular pigment.

The surplus volume of blue light required due to the absorption by

the pigment provides the benchmark for the optical density.

After the reference in the pigment free range of the parafovea at 7°

has been determined and calculated, the device indicates the optical density of the macular pigment.

 

 

Heterochromatic Flicker Photometry (HFP) and MPOD*
*MPOD = Macular Pigment Optical Density 

               Test
            FOVEA

  Test
  PARAFOVEA

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REFERENCES:

1.) List of Institutes that use the Densitometer!

2.) List of Publications based on Research with the Densitometer

Erlangen, 30. July. 2010
Prof. Welge-Lüßen puts the Densitometer (~ MacuLux®Science) for the University Hospital into use. (together with Dr. Schlomberg)

Waterford (Irland),
Institute of Vision Research,
Routine determination of MPOD 
in the area of research of 
Prof.Stephen Beatty and Dr.John Nolan

 

 

Cross sectional view of the macular Yellow: macular pigment.
MPOD (macular pigment density) contingent upon the distance from the center of the macula (in degrees of eccentricity) according to Hammond B.R. 1997